Tsai-Feng FUProfessor

B.S. in  Microbiology, Soochow University, 1994
M.S. in Tropical Medicine, National Yang-Ming University, 1996
Ph.D. in Biotechnology, National Tsing-Hua University,     2005

Postdoc Fellow, in Brain Research Center National Tsing-Hua University, 2005-2007
Assistant Professor, National Chi Nan University,2007-2013
Associate Professor, National Chi Nan University,2013-

Research Interests
Behavioral neurogenetics
Brain neuroscience
Bioimage

Google Scholar:
https://scholar.google.com.tw/citations?hl=zh-TW&user=glSpBjQAAAAJ

Selected Publications 代表著作
1. Yang DM, Fu TF, Lin CS, Chiu TY, Huang CC, Huang HY, Chung MW, Lin YS, Manurung RV,
Nguyen PNN, Chang YF. High-performance FRET biosensors for single-cell and in vivo lead
detection. Biosensors and Bioelectronics. 2020, 168:112571. (IF=10.257, R/C=1/86,
ANALYTICAL CHEMISTRY)
2. Lee WP, Chiang MH, Chang LY, Lee JY, Tsai YL, Chiu TH, Chiang HC, Fu TF, Wu T, Wu CL.
Mushroom body subsets encode CREB2-dependent water-reward long-term memory in Drosophila.
PLoS Genet. 2020, 16(8):e1008963. (IF=5.174; R/C=26/177, GENETICS & HEREDITY)
3. Yang DM, Manurung RV, Lin YS, Chiu TY, Lai WQ, Ch2ng YF, Fu TF. Monitoring the Heavy Metal
Lead Inside Living Drosophila with a FRET-Based Biosensor. Sensors. 2020 Mar 19;20(6):1712.
(IF=3.275; R/C=22/86, CHEMISTRY, ANALYTICAL)
4. Teng LL, Lu GL, Chiou LC, Lin WS, Cheng YY, Hsueh TE, Huang YC, Hwang NH, Yeh JW, Liao
RM, Fan SZ, Yen JH, Fu TF, Tsai TF, Wu MS, Wang PY. Serotonin receptor HTR6-mediated
mTORC1 signaling regulates dietary restriction-induced memory enhancement. PLoS Biology.
2019, 17(3):e2007097. (IF=7.076; R/C=6/93, BIOLOGY)
5. Shyu WH, Lee WP, Chiang MH, Chang CC, Fu TF, Chiang HC, Wu T, Wu CL. Electrical synapses

between mushroom body neurons are critical for consolidated memory retrieval in Drosophila. PLoS
Genetics. 2019, 15 (5):e1008153. (IF=5.174; R/C=26/177, GENETICS & HEREDITY)
6. Teng LL, Lu GL, Chiou LC, Lin WS, Cheng YY, Hsueh TE, Huang YC, Hwang NH, Yeh JW, Liao
RM, Fan SZ, Yen JH, Fu TF, Tsai TF, Wu MS, Wang PY. Serotonin receptor HTR6-mediated
mTORC1 signaling regulates dietary restriction-induced memory enhancement. PLoS Biology.
2019, 17(3):e2007097. (IF=7.076; R/C=6/93, BIOLOGY)
7. Lin WS, Yeh SR, Fan SZ, Chen LY, Yen JH, Fu TF, Wu MS, Wang PY. Insulin signaling in female
Drosophila links diet and sexual attractiveness. FASEB Journal. 2018, 32(7):3870-3877.
(IF=4.966; R/C=9/93, BIOLOGY)
8. Shyu WH, Chiu TH, Chiang MH, Cheng YC, Tsai YL, Fu TF, Wu T, Wu CL. Neural circuits for
long-term water-reward memory processing in thirsty Drosophila. Nature Communications. 2017,
8:15230. (IF=12.121; R/C=6/71, MULTIDISCIPLINARY SCIENCES)
9. Chen SL, Chen YH, Wang CC, Yu YW, Tsai YC, Hsu HW, Wu CL, Wang PY, Chen LC, Lan TH, Fu
TF*. Active and passive sexual roles that arise in Drosophila male-male courtship are modulated by
dopamine levels in PPL2ab neurons. Scientific Reports. 2017, 7:44595. (IF=3.998; R/C=17/71,
MULTIDISCIPLINARY SCIENCES)
10. Wu CL, Fu TF, Chiang MH, Chang YW, Her JL, Wu T. Magnetoreception Regulates Male
Courtship Activity in Drosophila. PLoS One. 2016, 11(5):e0155942. (IF=2.74; R/C=27/71,
MULTIDISCIPLINARY SCIENCES)
11. Yang CH, Shih MF, Chang CC, Chiang MH, Shih HW, Tsai YL, Chiang AS, Fu TF, Wu CL.
Additive Expression of Consolidated Memory through Drosophila Mushroom Body Subsets. PLoS
Genetics. 2016, 12(5):e1006061. (IF=5.174; R/C=26/177, GENETICS & HEREDITY)
12. Sun L, Wang PH, Lee CH, Fu TF, Chou MM, Hwang SF, Ke YM, Hsu ST, Lu CH. Clinical
parameters associated with absence of endocervical/transformation zone component in conventional
cervical Papanicolaou smears. Taiwan J Obstet Gynecol. 2016, 55(1):81-4. (IF=1.513;
R/C=63/82, OBSTETRICS & GYNECOLOGY)
13. Lin WS, Huang CW, Song YS, Yen JH, Kuo PC, Yeh SR, Lin HY, Fu TF, Wu MS, Wang HD,
Wang PY. Reduced Gut Acidity Induces an Obese-Like Phenotype in Drosophila melanogaster and in
Mice. PLoS One. 2015, 10 (10):e0139722. (IF=2.74; R/C=27/71, MULTIDISCIPLINARY
SCIENCES)
14. Huang CW, Wang HD, Bai H, Wu MS, Yen JH, Fu TF, Tatar M, Wang PY. Tequila regulates insulin-
like signaling and extends life span in Drosophila melanogaster. J Gerontol A Biol Sci Med Sci.
2015, 70 (12):1461-9 (IF=5.236; R/C=5/51, GERIATRICS & GERONTOLOGY)
15. Shih HW, Wu CL, Chang SW, Liu TH, Lai J SY, Fu TF, Fu CC, Chiang AS. Parallel circuits control
temperature preference in Drosophila during ageing. Nature Communications. 2015, 6:7775
(IF=12.121; R/C=6/71, MULTIDISCIPLINARY SCIENCES)
16. Kuo SY, Wu CL, Hsieh MY, Lin CT, Wen RK, Chen LC, Chen YH, Yu YW, Wang HD, Su YJ, Lin
CJ, Yang CY, Guan HY, Wang PY, Lan TH, Fu TF*. PPL2ab neurons restore sexual responses in
aged Drosophila males through dopamine. Nature Communications. 2015, 6:7490 (IF=12.121;
R/C=6/71, MULTIDISCIPLINARY SCIENCES)
17. Wu CL, Fu TF, Chou YY, Yeh SR. A single pair of neurons modulates egg-laying decisions in
Drosophila. PLoS One. 2015, 10(3), e0121335 (IF=2.74; R/C=27/71,
MULTIDISCIPLINARY SCIENCES)
18. Chin AL, Lin CY, Fu TF, Dickson BJ, Chiang AS. Diversity and wiring variability of visual local
neurons in the Drosophila medulla M6 stratum. J Comp Neurol. 2014, 522(17):3795-816 (IF:
2.801; R/C=9/168, ZOOLOGY)
19. Lin WS, Chen JY, Wang JC, Chen LY, Lin CH, Hsieh TR, Wang MF, Fu TF, Wang PY. The anti-
aging effects of Ludwigia octovalvis on Drosophila melanogaster and SAMP8 mice. Age. 2014,
36(2):689-703 (IF=4.684; R/C=14/51, GERIATRICS & GERONTOLOGY)
20. Lin HH, Chu LA, Fu TF, BJ Dickson, Chiang AS. Parallel Neural Pathways mediate CO2 avoidance

responses in Drosophila. Science. 2013, 340(6138): 1338-1341 (IF:41.845; R/C=2/71,
MULTIDISCIPLINARY SCIENCES)
21. Yeh TM, Liu SH, Lin KC, Kuo SY, Huang TY, Yen YR, Wen RK, Chen LC, Fu TF*. Dengue Virus
Enhances Thrombomodulin and ICAM-1 expression through the macrophage migration inhibitory
factor induction of the MAPK and PI3K signaling pathways. PLoS One. 2013, 8(1): e0055018
(IF=2.74; R/C=27/71, MULTIDISCIPLINARY SCIENCES)
22. Kuo SY, Tu CH, Hsu YT, Wang HD, Wen RK, Lin CT, Wu CL, Huang YT, Huang GS, Lan TH, Fu
TF*. A hormone receptor-based transactivator bridges different binary systems to precisely control
spatial-temporal gene expression in Drosophila. PLoS One. 2012, 7(12), e50855 (IF=2.74;
R/C=27/71, MULTIDISCIPLINARY SCIENCES)
23. Chen CC, Wu JK, Lin HW, Pai TP, Fu TF, Wu CL, Tully T, Chiang AS. Visualizing long-term
memory formation in two neurons of the Drosophila brain. Science. 2012, 335(6069): 678-685
(IF:41.845; R/C=2/71, MULTIDISCIPLINARY SCIENCES)
24. Lee PT, Lin HW, Chang YH, Fu TF, Dubnau J, Hirsh J and Chiang AS. A serotonin-mushroom body
circuit modulating memory formation in Drosophila. Proc Natl Acad Sci U S A. 2011,
108(33):13794-13799 (IF:9.412; R/C=8/71, MULTIDISCIPLINARY SCIENCES)
25. Lu CH, Chang CC, Chang MC, Chen SJ, Jan YJ, Fu TF, Ho ES. Clinical parameters associated with
unsatisfactory specimens of conventional cervical smears. Diagn Cytopathol. 2011, 39(2):87-91
(IF=1.229; R/C=21/29, MEDICAL LABORATORY TECHNOLOGY)
26. Lu CH, Chang CC, Ho ES, Chen SJ, Lin SJ, Fu TF, Chang MC. Should adequacy criteria in
cervicovaginal cytology be modified after radiotherapy, chemotherapy, or hysterectomy? Cancer
Cytopathol. 2010, 118(6):474-481 (IF=3.703; R/C=17/78, PATHOLOGY)
27. Wu CL*, Xia S*, Fu TF, Wang H, Chen B, Leong D, Chiang AS, and Tully T. NMDA receptors are
required for long-term memory formation outside of Drosophila mushroom body. Nature
Neuroscience. 2007, 10:1578-1586 (IF=20.071; R/C= 2/271, NEUROSCIENCES)
28. Xia S*, Miyashita T*, Fu TF*, Lin WY, Wu CL, Grady L, Lin IR, Saitoe M, Tully T, Chiang AS.
NMDA receptors mediate olfactory learning and memory in Drosophila. Current Biology. 2005,
15: 603-615 (*co-first author) (IF=9.601; R/C= 3/93, BIOLOGY)
29. Mu JJ, Tsay YG, Juan LJ, Fu TF, Huang WH, Chen DS, Chen PJ. The small delta antigen of
hepatitis delta virus is an acetylated protein and acetylation of lysine 72 may influence its cellular
localization and viral RNA synthesis. Virology. 2004, 319:60-7004 (IF=2.819; R/C= 30/37,
VIROLOGY)